Pingyu Yimeikang Plant Technology Co., Ltd

Product

Diosmin

Diosmin



Detailed


Name: Diosmin
CAS#: 520-27-4
Botanical Source: Immature bitter orange
Specification: EP, HPLC 90%--98%, Micronized Powder or Granule
Function & Application: Diosmin is a drug used to treat various symptoms related to the acute attack of hemorrhoids. It can also be used to treat various symptoms related to venous lymphatic insufficiency (feelling of heaviness of the legs, pain, soreness and discomfort in the morning).
 
TEST ITEM STANDARD RESULT
Appearance Greyish-yellow or light yellow hygroscopic powder Complies (Visual)
Melting point 277℃-278℃ Complies(Melting point apparatus)
Identification (a)(b) Must Positive Complies
Solubility    
 - in water Insoluble Complies
 - in dimethyl sulfoxide Soluble Complies
- alcohol Insoluble  
- dilute solutions of alkali hydroxides Soluble  
Residue on ignition ≤0.5% Complies
Mesh size 100% pass 80 mesh/2000 mesh Complies
Iodine ≤0.1% Complies (Potentiostat)
Related substances    
- acetoisovanillone ≤0.5% Complies (HPLC)
- hesperidin 4.0% Complies (HPLC)
- isorhoifolin 3.0% Complies (HPLC)
- 6-iododiosmin 0.6% Complies (HPLC)
- linarin 3.0% Complies (HPLC)
- diosmetin 2.0% Complies (HPLC)
- unspecified impurities 0.4% Complies (HPLC)
- total 8.5% Complies (HPLC)
Heavy metals 90%---102%  Complies (HPLC)
Water 6.0% Complies (K.F)
Residual solvents    
- methanol ≤3000ppm Complies (HPGC)
- acetic acid ≤5000ppm Complies (HPGC)
- pyridine ≤200ppm Complies (HPGC)
Assay    
MICROBIOLOGICAL TEST STANDARD RESULT
Total microbial count ≤1000cfu/g Complies
Yeast & mold ≤100cfu/g Complies
E.Coli Negative Negative
Salmonella Negative Negative
 
Packaging: The usual packaging is 25kg net carton drum or box with a polyethylene bag in side.
Storage: Preserve in well closed,light resistant and dry environment.


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